A Spatial Model of Tumor Growth with Cell Age, Cell Size, and Mutation of Cell Phenotypes

A model of tumor growth in a spatial environment is analyzed. The model includes proliferating and quiescent compartments of tumor cells indexed by successively mutated cell phenotypes of increasingly proliferative aggressiveness. The model incorporates spatial dependence due to both random motility...

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Bibliographic Details
Main Authors: Dyson, J, Villella-Bressan, R, Webb, G
Format: Journal article
Language:English
Published: 2007