Recognition of out-of-frame major histocompatibility complex class I-restricted epitopes in vivo.

In the course of constructing a recombinant vaccinia virus encoding the influenza A nucleoprotein (NP) gene preceded by the hemagglutinin leader sequence, we isolated a single base-pair deletion mutant which gave rise to L+NP(1-159) in which only the first 159 amino acids were in frame. Despite this...

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Bibliographic Details
Main Authors: Elliott, T, Bodmer, H, Townsend, A
Format: Journal article
Language:English
Published: 1996