Recognition of out-of-frame major histocompatibility complex class I-restricted epitopes in vivo.
In the course of constructing a recombinant vaccinia virus encoding the influenza A nucleoprotein (NP) gene preceded by the hemagglutinin leader sequence, we isolated a single base-pair deletion mutant which gave rise to L+NP(1-159) in which only the first 159 amino acids were in frame. Despite this...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1996
|