DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine.

We have prepared triplex-forming oligonucleotides containing the nucleotide analogue 5-dimethylaminopropargyl deoxyuridine (DMAPdU) in place of thymidine and examined their ability to form intermolecular triple helices by thermal melting and DNase I footprinting studies. The results were compared wi...

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Bibliographic Details
Main Authors: Rusling, D, Peng, G, Srinivasan, N, Fox, K, Brown, T
Format: Journal article
Language:English
Published: 2009