DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine.

We have prepared triplex-forming oligonucleotides containing the nucleotide analogue 5-dimethylaminopropargyl deoxyuridine (DMAPdU) in place of thymidine and examined their ability to form intermolecular triple helices by thermal melting and DNase I footprinting studies. The results were compared wi...

Полное описание

Библиографические подробности
Главные авторы: Rusling, D, Peng, G, Srinivasan, N, Fox, K, Brown, T
Формат: Journal article
Язык:English
Опубликовано: 2009