The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats
ATRX is a chromatin remodelling factor found at a wide range of tandemly repeated sequences including telomeres (TTAGGG)n. ATRX mutations are found in nearly all tumours that maintain their telomeres via the alternative lengthening of telomere (ALT) pathway, and ATRX is known to suppress this pathwa...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Journal article |
| Publicado em: |
EMBO Press
2017
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