Weighing-up protein dynamics: the combination of native mass spectrometry and molecular dynamics simulations

Structural dynamics underpin biological function at the molecular level, yet many biophysical and structural biology approaches give only a static or averaged view of proteins. Native mass spectrometry yields spectra of the many states and interactions in the structural ensemble, but its spatial res...

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Bibliographic Details
Main Authors: Marklund, E, Benesch, J
Format: Journal article
Language:English
Published: Elsevier 2019