Wnt secretion, trafficking and pathway activation: towards a structure-based understanding and modulation

<p>The Wnt pathway is a key morphogen route during embryonic development, regulating tissue organization, patterning and organ growth. In adult life, when maintained in a homeostatic range it controls stem cell self-renewal and regenerative processes, while its dysregulation promotes diseases...

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Détails bibliographiques
Auteur principal: Vecchia, L
Autres auteurs: Jones, E
Format: Thèse
Langue:English
Publié: 2021