Wnt secretion, trafficking and pathway activation: towards a structure-based understanding and modulation
<p>The Wnt pathway is a key morphogen route during embryonic development, regulating tissue organization, patterning and organ growth. In adult life, when maintained in a homeostatic range it controls stem cell self-renewal and regenerative processes, while its dysregulation promotes diseases...
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Format: | Thesis |
Language: | English |
Published: |
2021
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