Wnt secretion, trafficking and pathway activation: towards a structure-based understanding and modulation

<p>The Wnt pathway is a key morphogen route during embryonic development, regulating tissue organization, patterning and organ growth. In adult life, when maintained in a homeostatic range it controls stem cell self-renewal and regenerative processes, while its dysregulation promotes diseases...

Полное описание

Библиографические подробности
Главный автор: Vecchia, L
Другие авторы: Jones, E
Формат: Диссертация
Язык:English
Опубликовано: 2021