HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts.

BACKGROUND: In chronic HIV infection, antiretroviral therapy-induced normalization of CD4(+) T cell counts (immune reconstitution [IR]) is associated with a decreased incidence of opportunistic diseases. However, some individuals remain at risk for opportunistic diseases despite prolonged normaliza...

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Bibliographic Details
Main Authors: Gasser, O, Bihl, F, Wolbers, M, Loggi, E, Steffen, I, Hirsch, H, Günthard, H, Walker, B, Brander, C, Battegay, M, Hess, C
Format: Journal article
Language:English
Published: Public Library of Science 2007