Enhancing oncolytic virotherapy of glioblastoma by targeting innate immune ligands with a bispecific T cell engager
<p>Glioblastoma (GBM) is a highly aggressive brain tumour in adults, often becoming resistant towards conventional therapy of radiotherapy and temozolomide (TMZ) chemotherapy. The oncolytic herpes simplex virus-1 (oHSV- 1) G207 is a promising approach for GBM immunotherapy, capable of selectiv...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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