Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.
In response to DNA damage, eukaryotic cells must rapidly load DNA repair proteins onto damaged chromatin. Chromatin recruitment often entails ubiquitination of a damage-specific DNA repair protein, interaction with a ubiquitin binding factor, assembly of a multisubunit DNA repair complex, and eventu...
| Main Authors: | , |
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| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2008
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