Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.

In response to DNA damage, eukaryotic cells must rapidly load DNA repair proteins onto damaged chromatin. Chromatin recruitment often entails ubiquitination of a damage-specific DNA repair protein, interaction with a ubiquitin binding factor, assembly of a multisubunit DNA repair complex, and eventu...

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Bibliografske podrobnosti
Main Authors: Cohn, M, D'Andrea, A
Format: Journal article
Jezik:English
Izdano: 2008