Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform

Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform

Background Hydroxychloroquine has been shown to inhibit entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into epithelial cells in vitro, but clinical studies found no evidence of reduced mortality when treating patients with COVID-19. We aimed to evaluate the effectiveness of hy...

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Bibliographic Details
Main Authors: Rentsch, CT, DeVito, NJ, Bacon, S, MacKenna, B, Morton, CE, Bhaskaran, K, Brown, JP, Schultze, A, Hulme, WJ, Croker, R, Walker, AJ, Williamson, EJ, Bates, C, Mehrkar, A, Curtis, HJ, Evans, D, Wing, K, Inglesby, P, Mathur, R, Drysdale, H, Wong, AYS, McDonald, HI, Cockburn, J, Forbes, H, Parry, J, Hester, F, Harper, S, Smeeth, L, Douglas, IJ, Dixon, WG, Evans, SJW, Tomlinson, L, Goldacre, B
Format: Journal article
Language:English
Published: Elsevier 2020

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