Design and validation of an enzyme-linked immunospot assay for use in clinical trials of candidate HIV vaccines.

The enzyme-linked immunosorbent (ELISPOT) assay, which enumerates peripheral blood mononuclear cells (PBMCs) releasing interferon gamma (IFN-gamma) on specific antigen stimulation, is becoming the assay of choice for evaluation of vaccine-induced cell-mediated immune responses in many clinical trial...

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Main Authors: Mwau, M, Mcmichael, A, Hanke, T
格式: Journal article
语言:English
出版: 2002