Assessment of the value of therapeutic monitoring of tacrine in Alzheimer's disease.

OBJECTIVES: The purpose of this study was to validate the lower end of the putative therapeutic range of serum tacrine concentrations of 7-20 ng ml(-1) in the treatment of Alzheimer's disease. METHODS: The relationship between dose, steady-state serum tacrine concentrations and change in MMSE s...

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Hlavní autoři: Roberts, C, Ford, J, Truman, C, Scott, M, Mäkelä, P, Wilcock, G
Médium: Journal article
Jazyk:English
Vydáno: 1998