DeepC: Predicting 3D genome folding using megabase-scale transfer learning

Predicting the impact of noncoding genetic variation requires interpreting it in the context of three-dimensional genome architecture. We have developed deepC, a transfer-learning-based deep neural network that accurately predicts genome folding from megabase-scale DNA sequence. DeepC predicts domai...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Schwessinger, R, Gosden, M, Downes, D, Brown, RC, Oudelaar, AM, Telenius, J, Teh, YW, Lunter, G, Hughes, JR
Formatua: Journal article
Hizkuntza:English
Argitaratua: Springer Nature 2020