Modular Synthesis of Highly Substituted Pyridines via Enolate α-Alkenylation.
A novel methodology for the synthesis of highly substituted pyridines based on the palladium-catalyzed enolate α-alkenylation of ketones is presented; the formation of aromatic compounds is a new direction for this catalytic C-C bond forming reaction. In the key step, a protected β-haloalkenylaldehy...
| Autors principals: | , , |
|---|---|
| Format: | Journal article |
| Idioma: | English |
| Publicat: |
American Chemical Society
2015
|