Modular Synthesis of Highly Substituted Pyridines via Enolate α-Alkenylation.
A novel methodology for the synthesis of highly substituted pyridines based on the palladium-catalyzed enolate α-alkenylation of ketones is presented; the formation of aromatic compounds is a new direction for this catalytic C-C bond forming reaction. In the key step, a protected β-haloalkenylaldehy...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Chemical Society
2015
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