Modular Synthesis of Highly Substituted Pyridines via Enolate α-Alkenylation.

A novel methodology for the synthesis of highly substituted pyridines based on the palladium-catalyzed enolate α-alkenylation of ketones is presented; the formation of aromatic compounds is a new direction for this catalytic C-C bond forming reaction. In the key step, a protected β-haloalkenylaldehy...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hardegger, L, Habegger, J, Donohoe, T
التنسيق: Journal article
اللغة:English
منشور في: American Chemical Society 2015