Single dose pharmacokinetics of proguanil and its metabolites in healthy subjects.
1. Plasma and whole blood concentrations of proguanil and its two major metabolites cycloguanil (CG) and 4-chlorophenylbiguanide (CPB) were measured by a sensitive h.p.l.c. technique in nine healthy adult male volunteers after a single oral dose of proguanil 200 mg. 2. Proguanil was absorbed with a...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1987
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