HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells
<h4>Background</h4> <p>T follicular helper (Tfh) cells are increasingly recognized as a major reservoir of HIV infection that will likely need to be addressed in approaches to curing HIV. However, Tfh express minimal CCR5, the major coreceptor for HIV-1, and the mechanism by which...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2017
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