HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells

<h4>Background</h4> <p>T follicular helper (Tfh) cells are increasingly recognized as a major reservoir of HIV infection that will likely need to be addressed in approaches to curing HIV. However, Tfh express minimal CCR5, the major coreceptor for HIV-1, and the mechanism by which...

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Hlavní autoři:	Xu, Y, Phetsouphanh, C, Suzuki, K, Aggrawal, A, Graff-Dubois, S, Roche, M, Bailey, M, Alcantara, S, Cashin, K, Sivasubramaniam, R, Koelsch, K, Autran, B, Harvey, R, Gorry, P, Moris, A, Cooper, D, Turville, S, Kent, S, Kelleher, A, Zaunders, J
Médium:	Journal article
Jazyk:	English
Vydáno:	Frontiers Media 2017

HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells

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