Sister DNA entrapment between juxtaposed Smc heads and kleisin of the cohesin complex

Cohesin entraps sister DNAs within tripartite rings created by pairwise interactions between Smc1, Smc3, and Scc1. Because Smc1/3 ATPase heads can also interact with each other, cohesin rings have the potential to form a variety of sub-compartments. Using in vivo cysteine cross-linking, we show that...

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Bibliographic Details
Main Authors: Chapard, C, Jones, R, van Oepen, T, Scheinost, J, Nasmyth, K
Format: Journal article
Published: Cell Press 2019