Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin.

BACKGROUND: Impaired vitamin B(12) function and decreased vitamin B(12) status have been associated with neurological and cognitive impairment. Current assays analyze total vitamin B(12) concentration, only a small percentage of which is metabolically active. Concentrations of this active component,...

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Bibliographic Details
Main Authors: Clarke, R, Sherliker, P, Hin, H, Nexo, E, Hvas, A, Schneede, J, Birks, J, Ueland, P, Emmens, K, Scott, J, Molloy, A, Evans, J
Format: Journal article
Language:English
Published: 2007