Antidopaminergic effects of dietary tyrosine depletion in healthy subjects and patients with manic illness.

BACKGROUND: In rats, amino acid mixtures lacking tyrosine and its precursor phenylalanine decrease the release of dopamine produced by the psychostimulant drug amphetamine. Amphetamine has been proposed as a model for clinical mania. AIMS: To assess whether dietary tyrosine depletion attenuates the...

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Bibliographic Details
Main Authors: McTavish, S, McPherson, M, Harmer, C, Clark, L, Sharp, T, Goodwin, G, Cowen, P
Format: Journal article
Language:English
Published: 2001