The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy.

CONTEXT: Thyroid-associated ophthalmopathy (TAO) is a sight-threatening autoimmune disease in which de novo adipogenesis has been identified as a fundamental pathogenic mechanism. 11beta-Hydroxysteroid dehydrogenase 1 (11beta-HSD1) increases cortisol bioavailability and is pivotal in mediating gluco...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Tomlinson, J, Durrani, O, Bujalska, I, Gathercole, L, Tomlins, P, Reuser, T, Rose, G, Curnow, S, Stewart, P, Walker, E, Rauz, S
פורמט: Journal article
שפה:English
יצא לאור: 2010