Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells.

T cells interacting with antigen-presenting cells (APCs) form an "immunological synapse" (IS), a bull's-eye pattern composed of a central supramolecular activation cluster enriched with T cell receptors (TCRs) surrounded by a ring of adhesion molecules (a peripheral supramolecular act...

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Bibliographic Details
Main Authors: Kaizuka, Y, Douglass, A, Varma, R, Dustin, M, Vale, R
Format: Journal article
Language:English
Published: 2007