Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.

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Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely unknown. Here we perform a meta-analysis of 11 genome-wide association case-control data sets, totalling 17,045 endometrio...

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Hauptverfasser: Sapkota, Y, Steinthorsdottir, V, Morris, AP, Fassbender, A, Rahmioglu, N, De Vivo, I, Buring, JE, Zhang, F, Edwards, TL, Jones, S, O, D, Peterse, D, Rexrode, KM, Ridker, PM, Schork, AJ, MacGregor, S, Martin, NG, Becker, CM, Adachi, S, Yoshihara, K, Enomoto, T, Takahashi, A, Kamatani, Y, Matsuda, K, Kubo, M, Thorleifsson, G, Geirsson, RT, Thorsteinsdottir, U, Wallace, LM, iPSYCH-SSI-Broad Group, Yang, J, Edwards, DR, Nyegaard, M, Low, SK, Zondervan, KT, Missmer, SA, D'Hooghe, T, Montgomery, GW, Chasman, DI, Stefansson, K, Tung, JY, Nyholt, DR
Format: Journal article
Sprache:English
Veröffentlicht: Springer Nature 2017
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