Posttranslational and therapeutic control of gasdermin-mediated pyroptosis and inflammation
Pyroptosis is a proinflammatory form of cell death, mediated by membrane pore-forming proteins called gasdermins. Gasdermin pores allow the release of the pro-inflammatory cytokines IL-1β and IL-18 and cause cell swelling and cell lysis leading to release of other intracellular proteins that act as...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Frontiers Media
2021
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