Posttranslational and therapeutic control of gasdermin-mediated pyroptosis and inflammation

Pyroptosis is a proinflammatory form of cell death, mediated by membrane pore-forming proteins called gasdermins. Gasdermin pores allow the release of the pro-inflammatory cytokines IL-1β and IL-18 and cause cell swelling and cell lysis leading to release of other intracellular proteins that act as...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Fischer, FA, Chen, KW, Bezbradica, JS
التنسيق: Journal article
اللغة:English
منشور في: Frontiers Media 2021