Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli.

A triazole mimic of a DNA phosphodiester linkage has been produced by templated chemical ligation of oligonucleotides functionalized with 5'-azide and 3'-alkyne. The individual azide and alkyne oligonucleotides were synthesized by standard phosphoramidite methods and assembled using a stra...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: El-Sagheer, A, Sanzone, A, Gao, R, Tavassoli, A, Brown, T
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2011