Function, phenotype and development of human CD161+CD8 T cells

Tc17 cells and the semi-invariant human mucosal associated invariant T (MAIT) cells are important CD8+ tissue-homing cell populations. Both are characterized by high expression of CD161 (++) and type-17 differentiation, yet their origins and relationships remain poorly defined. By transcriptional an...

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Bibliographic Details
Main Author: Walker, LJ
Other Authors: Klenerman, P
Format: Thesis
Language:English
Published: 2012
Subjects: