Probing biomolecular structures and dynamics of single molecules using in-gel alternating-laser excitation.

Gel electrophoresis is a standard biochemical technique used for separating biomolecules on the basis of size and charge. Despite the use of gels in early single-molecule experiments, gel electrophoresis has not been widely adopted for single-molecule fluorescence spectroscopy. We present a novel me...

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Bibliographic Details
Main Authors: Santoso, Y, Kapanidis, A
Format: Journal article
Language:English
Published: 2009