Primaquine dose and the risk of haemolysis in patients with uncomplicated Plasmodium vivax malaria: a systematic review and individual patient data meta-analysis

<p><strong>Background:</strong> Primaquine radical cure is used to treat dormant liver-stage parasites and prevent relapsing Plasmodium vivax malaria but is limited by concerns of haemolysis. We undertook a systematic review and individual patient data meta-analysis to investigate...

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Main Authors: Rajasekhar, M, Simpson, JA, Ley, B, Edler, P, Chu, CS, Abreha, T, Awab, GR, Baird, JK, Bancone, G, Barber, BE, Grigg, MJ, Hwang, J, Karunajeewa, H, Lacerda, MVG, Ladeia-Andrade, S, Llanos-Cuentas, A, Pukrittayakamee, S, Rijal, KR, Saravu, K, Sutanto, I, Taylor, WRJ, Thriemer, K, Watson, JA, Guerin, PJ, White, NJ, Commons, RJ, Price, RN, WorldWide Antimalarial Resistance Network (WWARN) Vivax Primaquine Dosing Efficacy, Tolerability and Safety Study Group
Format: Journal article
Language:English
Published: Elsevier 2023