Hidden heritability due to heterogeneity across seven populations

The genome-wide association studies (GWAS) dominating genetic discovery are based on large meta-analyses that combine data from diverse historical time periods and populations. Polygenic scores constructed from GWAS explain only a fraction of the heritability derived from twin and whole-genome studi...

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Detalhes bibliográficos
Main Authors: Tropf, FC, Lee, SH, Verweij, RM, Stulp, G, van der Moost, PJ, de Vlaming, R, Bakshi, A, Briley, DA, Rahal, C, Hellpap, R, Nyman, A, Esko, T, Metspalu, A, Medland, SE, Martin, NG, Barban, N, Snieder, H, Robinson, MR, Mills, MC
Formato: Journal article
Publicado em: Springer Nature 2017