Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions

Human macrophages are specialised hosts for HIV-1, dengue virus, Leishmania and Mycobacterium tuberculosis. Yet macrophage research is hampered by lack of appropriate cell models for modelling infection by these human pathogens, because available myeloid cell lines are, by definition, not terminally...

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Bibliographic Details
Main Authors: van Wilgenburg, B, Browne, C, Vowles, J, Cowley, S
Format: Journal article
Language:English
Published: Public Library of Science 2013