Elucidating the factors required for activation of the alternative lengthening of telomeres pathway
<p>A key hallmark of cancers is their ability to divide indefinitely through a process termed immortalisation, in which a telomere maintenance mechanism (TMM) is activated. Whilst many cancers upregulate the reverse transcriptase telomerase, between 10-15% utilise the alternative lengthening o...
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| Format: | Thesis |
| Language: | English |
| Published: |
2023
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