Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study

<p><b>Background</b></p> Analysis of circulating tumour DNA could stratify cancer risk in symptomatic patients. We aimed to evaluate the performance of a methylation-based multicancer early detection (MCED) diagnostic test in symptomatic patients referred from primary care. &...

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Bibliographic Details
Main Authors: Nicholson, BD, Oke, J, Virdee, PS, Harris, DA, O'Doherty, C, Park, JES, Hamady, Z, Sehgal, V, Millar, A, Medley, L, Tonner, S, Vargova, M, Engonidou, L, Riahi, K, Luan, Y, Hiom, S, Kumar, H, Nandani, H, Kurtzman, KN, Yu, L-M, Freestone, C, Pearson, S, Hobbs, FR, Perera, R, Middleton, MR
Format: Journal article
Language:English
Published: Elsevier 2023