Transcription initiation activity sets replication origin efficiency in mammalian cells.

Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sequeira-Mendes, J, Diaz-Uriarte, R, Apedaile, A, Huntley, D, Brockdorff, N, Gomez, M
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2009

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