Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

Post-inflammatory behaviours in rodents are widely used to model human depression and to test the efficacy of novel anti-depressants. Mice injected with lipopolysaccharide (LPS) display a depressive-like phenotype twenty-four hours after endotoxin administration. Despite the widespread use of this m...

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Bibliographic Details
Main Authors: Chan, SY, Probert, F, Radford-Smith, D, Hebert, J, Claridge, T, Anthony, D, Burnet, P
Format: Journal article
Language:English
Published: Springer Nature 2020