Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue.

Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue.

CONTEXT: Glucocorticoid (GC) excess is characterized by central obesity, insulin resistance, and in some cases, type 2 diabetes. However, the impact of GC upon insulin signaling in human adipose tissue has not been fully explored. OBJECTIVE: We have examined the effect of GC upon insulin signaling i...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Gathercole, L, Bujalska, I, Stewart, P, Tomlinson, J
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2007

Ижил төстэй зүйлс

Short- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue.
-н: Gathercole, L, зэрэг
Хэвлэсэн: (2011)

Glucocorticoid and Insulin Regulation of Lipogenesis in Human Adipose Tissue.
-н: Gathercole, L, зэрэг
Хэвлэсэн: (2010)

Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
-н: Gathercole, L, зэрэг
Хэвлэсэн: (2011)

Glucocorticoid and insulin regulation of lipogenesis in human adipose tissue
-н: Gathercole, L, зэрэг
Хэвлэсэн: (2010)

Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo.
-н: Hazlehurst, J, зэрэг
Хэвлэсэн: (2013)

Impact of Glucocorticoids upon Lipogenesis and beta-Oxidation in Skeletal Muscle.
-н: Morgan, SA, зэрэг
Хэвлэсэн: (2010)

Expression profiling of 11beta-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subcutaneous and omental human preadipocytes.
-н: Bujalska, I, зэрэг
Хэвлэсэн: (2006)

Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat.
-н: Bujalska, I, зэрэг
Хэвлэсэн: (2007)

Subcutaneous adipose tissue insulin resistance and lipolysis in patients with nonalcoholic steatohepatitis
-н: Armstrong, M, зэрэг
Хэвлэсэн: (2013)

11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess.
-н: Morgan, SA, зэрэг
Хэвлэсэн: (2014)

Reduced glucocorticoid production rate, decreased 5alpha-reductase activity, and adipose tissue insulin sensitization after weight loss.
-н: Tomlinson, J, зэрэг
Хэвлэсэн: (2008)

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.
-н: Tomlinson, J, зэрэг
Хэвлэсэн: (2002)

Depot-specific prostaglandin synthesis in human adipose tissue: a novel possible mechanism of adipogenesis.
-н: Quinkler, M, зэрэг
Хэвлэсэн: (2006)

Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis
-н: Armstrong, M, зэрэг
Хэвлэсэн: (2014)

Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis.
-н: Armstrong, M, зэрэг
Хэвлэсэн: (2014)

Role of Subcutaneous Adipose Tissue in the Pathogenesis of Insulin Resistance
-н: Pavankumar Patel, зэрэг
Хэвлэсэн: (2013-01-01)

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.
-н: Morgan, SA, зэрэг
Хэвлэсэн: (2009)

11β-HSD1 modulates the set point of brown adipose tissue response to glucocorticoids in male mice
-н: Doig, C, зэрэг
Хэвлэсэн: (2017)

Increased central adiposity and decreased subcutaneous adipose tissue 11β‐hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance—A longitudinal cohort study
-н: Crowley, R, зэрэг
Хэвлэсэн: (2019)

Subcutaneous adipose tissue classification
-н: A. Sbarbati, зэрэг
Хэвлэсэн: (2010-11-01)

Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle.
-н: Morgan, SA, зэрэг
Хэвлэсэн: (2013)

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
-н: Tomlinson, J, зэрэг
Хэвлэсэн: (2004)

5α-reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes
-н: Nasiri, M, зэрэг
Хэвлэсэн: (2015)

Evidence for glycerol uptake by subcutaneous adipose tissue.
-н: Samra, J, зэрэг
Хэвлэсэн: (1999)

Remodeling phenotype of human subcutaneous adipose tissue macrophages.
-н: Bourlier, V, зэрэг
Хэвлэсэн: (2008)

Modulation of glucocorticoid action and the treatment of type-2 diabetes.
-н: Tomlinson, J, зэрэг
Хэвлэсэн: (2007)

Regulation of human subcutaneous adipose tissue blood flow
-н: Frayn, K, зэрэг
Хэвлэсэн: (2014)

Regulation of human subcutaneous adipose tissue blood flow.
-н: Frayn, K, зэрэг
Хэвлэсэн: (2014)

Secretion of autoimmune antibodies in the human subcutaneous adipose tissue.
-н: Daniela Frasca, зэрэг
Хэвлэсэн: (2018-01-01)

Expression of Genes Related to Prostaglandin Synthesis or Signaling in Human Subcutaneous and Omental Adipose Tissue: Depot Differences and Modulation by Adipogenesis
-н: Andréanne Michaud, зэрэг
Хэвлэсэн: (2014-01-01)

Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.
-н: Bujalska, I, зэрэг
Хэвлэсэн: (2008)

Comprehensive assessment of expression of insulin signaling pathway components in subcutaneous adipose tissue of women with and without polycystic ovary syndrome
-н: Ning Xu, зэрэг
Хэвлэсэн: (2015-09-01)

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.
-н: Quinkler, M, зэрэг
Хэвлэсэн: (2004)

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.
-н: Tomlinson, J, зэрэг
Хэвлэсэн: (2007)

Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
-н: Tomlinson, J, зэрэг
Хэвлэсэн: (2001)

Amino acid metabolism in human subcutaneous adipose tissue in vivo.
-н: Frayn, K, зэрэг
Хэвлэсэн: (1991)

Keratinocyte progenitor cells reside in human subcutaneous adipose tissue.
-н: Toshio Hasegawa, зэрэг
Хэвлэсэн: (2015-01-01)

MicroRNA expression in human omental and subcutaneous adipose tissue.
-н: Nora Klöting, зэрэг
Хэвлэсэн: (2009-01-01)

Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake.
-н: McNelis, J, зэрэг
Хэвлэсэн: (2013)

Expression of lipoprotein lipase in different human subcutaneous adipose tissue regions
-н: P Arner, зэрэг
Хэвлэсэн: (1991-03-01)