Purging in auto- and allografts: monoclonal antibodies which use human complement and other natural effector mechanisms.

CAMPATH-1M is a rat IgM monoclonal antibody which binds to an antigen on all human lymphocytes and monocytes, but which is not present on marrow stem cells (Hale et al., 1983). Lymphocytes can be efficiently killed in bone marrow buffy coat preparations using the antibody and donor human serum as a...

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Bibliographic Details
Main Authors: Cobbold, S, Hale, G, Clark, MR, Waldmann, H
Format: Journal article
Language:English
Published: 1990