Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8+ T cell response

Psoriasis is a complex inflammatory skin disease affecting ∼3% of the population worldwide. Although type I interferons (IFN-I) are thought to be involved in its pathogenesis, the details of this relationship remain elusive. Here we show that in a murine model of imiquimod-driven psoriatic skin infl...

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Bibliographic Details
Main Authors: Stockenhuber, K, Hegazy, A, West, N, Ilott, N, Stockenhuber, A, Bullers, S, Thornton, E, Arnold, I, Tucci, A, Waldmann, H, Ogg, G, Powrie, F
Format: Journal article
Language:English
Published: Rockefeller University Press 2018