Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides

Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides

<p>Telomerase represents an attractive target in oncology as it is expressed in cancer but not in normal tissues. The oligonucleotide inhibitors of telomerase represent a promising anticancer strategy, although poor cellular uptake can restrict their efficacy. In this study, gold nanoparticles...

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מידע ביבליוגרפי
Main Authors: Bavelaar, BM, Song, L, Jackson, MR, Able, S, Tietz, O, Skaripa-Koukelli, I, Waghorn, PA, Gill, MR, Carlisle, RC, Tarsounas, M, Vallis, KA
פורמט: Journal article
שפה:English
יצא לאור: American Chemical Society 2021

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