Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.

Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.

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Genome-wide association (GWA) studies have proved extremely successful in identifying novel genetic loci contributing effects to complex human diseases. In doing so, they have highlighted the fact that many potential loci of modest effect remain undetected, partly due to the need for samples consist...

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Xehetasun bibliografikoak
Egile Nagusiak:	Zhuang, J, Zondervan, K, Nyberg, F, Harbron, C, Jawaid, A, Cardon, L, Barratt, B, Morris, A
Formatua:	Conference item
Argitaratua:	2010

Antzeko izenburuak

Optimizing the Power of Genome-Wide Association Studies by Using Publicly Available Reference Samples to Expand the Control Group
nork: Zhuang, J, et al.
Argitaratua: (2010)

Optimising the power of genome-wide association studies by using publicly available reference samples to expand the controls group
nork: Zhuang, J, et al.
Argitaratua: (2009)

Designing candidate gene and genome-wide case-control association studies.
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Two-stage two-locus models in genome-wide association.
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Argitaratua: (2006)

Two-stage two-locus models in genome-wide association.
nork: Evans, D, et al.
Argitaratua: (2006)

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Beyond endometriosis genome-wide association study: from genomics to phenomics to the patient
nork: Zondervan, K, et al.
Argitaratua: (2016)

The use of genome-wide eQTL associations to identify novel genetic pathways involved in complex traits
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Determinants of success in genetic association studies of complex traits.
nork: Zondervan, K, et al.
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Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
nork: Pettersson, F, et al.
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Discovery of novel loci for endometriosis in genome-wide association analysis of 63 K cases and 700 K controls
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Two-stage two-locus models in genome-wide association.
nork: David M Evans, et al.
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Large-scale integrated genome-wide RNA sequencing, miRNA array, and genomic analyses to unravel the functionality of genome-wide association results in endometriosis
nork: Rahmioglu, N, et al.
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Commercially available outbred mice for genome-wide association studies.
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Report on available standard samples, reference samples, and high-purity materials for spectrochemical analysis/
nork: Michaelis, Robert E., et al.
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An expanded genome-wide association study of type 2 diabetes in Europeans
nork: Scott, RA, et al.
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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
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Genome-wide genetic analyses highlight MAPK signalling in the pathogenesis of endometriosis
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Molecular analysis and genome discovery /
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Commercially available outbred mice for genome-wide association studies.
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Assessment of sex-specific effects in a genome-wide association study of rheumatoid arthritis
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Genome-wide impact of a recently expanded microRNA cluster in mouse
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Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
nork: Barnes Michael R, et al.
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Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets.
nork: Rahmioglu, N, et al.
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Genome-wide expanding of genetic evolution and potential pathogenicity in Vibrio alginolyticus
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Genome-wide associations for birth weight and correlations with adult disease
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Genome-wide strategies for detecting multiple loci that influence complex diseases.
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Temporal trends in results availability from genome-wide association studies.
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The impact of expanded telehealth availability on primary care utilization
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Polyglutamine Expanded Huntingtin Dramatically Alters the Genome-Wide Binding of HSF1
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Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis
nork: Uimari, O, et al.
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A genome-wide screen for quantitative trait loci involved in developmental dyslexia in a large sample of sib-pairs from the UK
nork: Francks, C, et al.
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Genetics-Based Classification of Filoviruses Calls for Expanded Sampling of Genomic Sequences
nork: Alexander E. Gorbalenya, et al.
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Erratum: The complex interplay among factors that influence allelic association (Nature Reviews Genetics (2004) 5 (89-100) DOI: 10.1038/nrg1270)
nork: Zondervan, K, et al.
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The complex interplay among factors that influence allelic association.
nork: Zondervan, K, et al.
Argitaratua: (2004)

The complex interplay among factors that influence allelic association (vol 5, pg 89, 2004)
nork: Zondervan, K, et al.
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Evaluating results from genome-wide linkage scans of complex discrete traits by locus counting.
nork: Wiltshire, S, et al.
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