Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.

Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.

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Genome-wide association (GWA) studies have proved extremely successful in identifying novel genetic loci contributing effects to complex human diseases. In doing so, they have highlighted the fact that many potential loci of modest effect remain undetected, partly due to the need for samples consist...

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Manylion Llyfryddiaeth
Prif Awduron:	Zhuang, J, Zondervan, K, Nyberg, F, Harbron, C, Jawaid, A, Cardon, L, Barratt, B, Morris, A
Fformat:	Conference item
Cyhoeddwyd:	2010

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Optimizing the Power of Genome-Wide Association Studies by Using Publicly Available Reference Samples to Expand the Control Group
gan: Zhuang, J, et al.
Cyhoeddwyd: (2010)

Optimising the power of genome-wide association studies by using publicly available reference samples to expand the controls group
gan: Zhuang, J, et al.
Cyhoeddwyd: (2009)

Designing candidate gene and genome-wide case-control association studies.
gan: Zondervan, K, et al.
Cyhoeddwyd: (2007)

Using combined datasets to find true associations in genome wide association studies
gan: Barrett, J, et al.
Cyhoeddwyd: (2007)

Two-stage two-locus models in genome-wide association.
gan: Evans, D, et al.
Cyhoeddwyd: (2006)

Two-stage two-locus models in genome-wide association.
gan: Evans, D, et al.
Cyhoeddwyd: (2006)

Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms.
gan: Anderson, C, et al.
Cyhoeddwyd: (2008)

Beyond endometriosis genome-wide association study: from genomics to phenomics to the patient
gan: Zondervan, K, et al.
Cyhoeddwyd: (2016)

The use of genome-wide eQTL associations to identify novel genetic pathways involved in complex traits
gan: Min, J, et al.
Cyhoeddwyd: (2008)

Determinants of success in genetic association studies of complex traits.
gan: Zondervan, K, et al.
Cyhoeddwyd: (2003)

Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
gan: Pettersson, F, et al.
Cyhoeddwyd: (2008)

Discovery of novel loci for endometriosis in genome-wide association analysis of 63 K cases and 700 K controls
gan: Rahmioglu, N, et al.
Cyhoeddwyd: (2018)

Two-stage two-locus models in genome-wide association.
gan: David M Evans, et al.
Cyhoeddwyd: (2006-09-01)

Large-scale integrated genome-wide RNA sequencing, miRNA array, and genomic analyses to unravel the functionality of genome-wide association results in endometriosis
gan: Rahmioglu, N, et al.
Cyhoeddwyd: (2017)

Commercially available outbred mice for genome-wide association studies.
gan: Yalcin, B, et al.
Cyhoeddwyd: (2010)

Report on available standard samples, reference samples, and high-purity materials for spectrochemical analysis/
gan: Michaelis, Robert E., et al.
Cyhoeddwyd: (1963)

An expanded genome-wide association study of type 2 diabetes in Europeans
gan: Scott, RA, et al.
Cyhoeddwyd: (2017)

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
gan: Zeggini, E, et al.
Cyhoeddwyd: (2007)

Genome-wide genetic analyses highlight MAPK signalling in the pathogenesis of endometriosis
gan: UImari, O, et al.
Cyhoeddwyd: (2017)

Molecular analysis and genome discovery /
gan: Rapley, Ralph, et al.
Cyhoeddwyd: (2004)

Commercially available outbred mice for genome-wide association studies.
gan: Binnaz Yalcin, et al.
Cyhoeddwyd: (2010-09-01)

Assessment of sex-specific effects in a genome-wide association study of rheumatoid arthritis
gan: Zhuang, J, et al.
Cyhoeddwyd: (2009)

Genome-wide impact of a recently expanded microRNA cluster in mouse
gan: Zheng, Grace X. Y., et al.
Cyhoeddwyd: (2012)

Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
gan: Barnes Michael R, et al.
Cyhoeddwyd: (2008-03-01)

Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets.
gan: Rahmioglu, N, et al.
Cyhoeddwyd: (2014)

Genome-wide expanding of genetic evolution and potential pathogenicity in Vibrio alginolyticus
gan: Zhenzhou Huang, et al.
Cyhoeddwyd: (2024-12-01)

Genome-wide associations for birth weight and correlations with adult disease
gan: Horikoshi, M, et al.
Cyhoeddwyd: (2016)

Genome-wide strategies for detecting multiple loci that influence complex diseases.
gan: Marchini, J, et al.
Cyhoeddwyd: (2005)

Temporal trends in results availability from genome-wide association studies.
gan: Andrew D Johnson, et al.
Cyhoeddwyd: (2011-09-01)

The impact of expanded telehealth availability on primary care utilization
gan: Ram A. Dixit, et al.
Cyhoeddwyd: (2022-09-01)

Polyglutamine Expanded Huntingtin Dramatically Alters the Genome-Wide Binding of HSF1
gan: Riva, Laura, et al.
Cyhoeddwyd: (2014)

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis
gan: Uimari, O, et al.
Cyhoeddwyd: (2017)

A genome-wide screen for quantitative trait loci involved in developmental dyslexia in a large sample of sib-pairs from the UK
gan: Francks, C, et al.
Cyhoeddwyd: (2000)

Genetics-Based Classification of Filoviruses Calls for Expanded Sampling of Genomic Sequences
gan: Alexander E. Gorbalenya, et al.
Cyhoeddwyd: (2012-08-01)

Erratum: The complex interplay among factors that influence allelic association (Nature Reviews Genetics (2004) 5 (89-100) DOI: 10.1038/nrg1270)
gan: Zondervan, K, et al.
Cyhoeddwyd: (2004)

The complex interplay among factors that influence allelic association.
gan: Zondervan, K, et al.
Cyhoeddwyd: (2004)

The complex interplay among factors that influence allelic association (vol 5, pg 89, 2004)
gan: Zondervan, K, et al.
Cyhoeddwyd: (2004)

Evaluating results from genome-wide linkage scans of complex discrete traits by locus counting.
gan: Wiltshire, S, et al.
Cyhoeddwyd: (2002)

An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank
gan: Smith, SM, et al.
Cyhoeddwyd: (2021)

Genome-wide characterization and comparison of endogenous retroviruses among 3 duck reference genomes
gan: Yuan Bai, et al.
Cyhoeddwyd: (2024-05-01)