A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH.

We analysed chromosome 16q in 106 breast cancers using tiling-path array-comparative genomic hybridization (aCGH). About 80% of ductal cancers (IDCs) and all lobular cancers (ILCs) lost at least part of 16q. Grade I (GI) IDCs and ILCs often lost the whole chromosome arm. Grade II (GII) and grade III...

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Main Authors: Roylance, R, Gorman, P, Papior, T, Wan, Y, Ives, M, Watson, J, Collins, C, Wortham, N, Langford, C, Fiegler, H, Carter, N, Gillett, C, Sasieni, P, Pinder, S, Hanby, A, Tomlinson, I
Format: Journal article
Jezik:English
Izdano: 2006