Divergent Memory B Cell Responses in a Mixed Infant Pneumococcal Conjugate Vaccine Schedule

BACKGROUND: Vaccine-induced immunity against pneumococcal infection relies on the generation of high concentrations of antibody and B-cell memory. Both the 10- and the 13-valent pneumococcal conjugate vaccines (PCV-10 and PCV-13) effectively reduce disease caused by vaccine serotypes. It is unknown...

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Bibliographic Details
Main Authors: Trück, J, Mitchell, R, Jawad, S, Clutterbuck, E, Snape, M, Kelly, D, Voysey, M, Pollard, A
Format: Journal article
Language:English
Published: Wolters Kluwer Health, Inc. 2016