Genetic architecture of quantitative traits in mice, flies, and humans.

Genetic architecture of quantitative traits in mice, flies, and humans.

We compare and contrast the genetic architecture of quantitative phenotypes in two genetically well-characterized model organisms, the laboratory mouse, Mus musculus, and the fruit fly, Drosophila melanogaster, with that found in our own species from recent successes in genome-wide association studi...

Descripció completa

Dades bibliogràfiques
Autors principals:	Flint, J, Mackay, T
Format:	Journal article
Idioma:	English
Publicat:	2009

Ítems similars

Dissecting quantitative traits in mice.
per: Mott, R, et al.
Publicat: (2013)

The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis.
per: Wen Huang, et al.
Publicat: (2016-11-01)

Do animal models have a place in the genetic analysis of quantitative human behavioural traits?
per: Flint, J, et al.
Publicat: (1996)

Mapping quantitative traits and strategies to find quantitative trait genes.
per: Flint, J
Publicat: (2011)

Q&A: Genetic analysis of quantitative traits
per: Mackay Trudy FC
Publicat: (2009-04-01)

Simultaneous detection and fine mapping of quantitative trait loci in mice using heterogeneous stocks.
per: Mott, R, et al.
Publicat: (2002)

Dissecting the genetic architecture of human personality.
per: Munafò, MR, et al.
Publicat: (2011)

Dissecting the genetic architecture of human personality
per: Munafò, MR, et al.
Publicat: (2011)

Using progenitor strain information to identify quantitative trait nucleotides in outbred mice.
per: Yalcin, B, et al.
Publicat: (2005)

High-resolution mapping of quantitative trait loci in outbred mice.
per: Talbot, C, et al.
Publicat: (1999)

Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.
per: Yalcin, B, et al.
Publicat: (2004)

Genetic and environmental effects on complex traits in mice.
per: Valdar, W, et al.
Publicat: (2006)

High-resolution mapping of quantitative trait loci for emotionality in selected strains of mice.
per: Turri, MG, et al.
Publicat: (1999)

Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2
per: Menzel, S, et al.
Publicat: (2014)

Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2.
per: Menzel, S, et al.
Publicat: (2014)

Analysis of quantitative trait loci that influence animal behavior.
per: Flint, J
Publicat: (2003)

Multivariate analysis of quantitative trait loci influencing variation in anxiety-related behavior in laboratory mice.
per: Turri, MG, et al.
Publicat: (2004)

Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice
per: Spiezio Sabrina H, et al.
Publicat: (2012-05-01)

Mapping complex traits in heterogeneous stock mice
per: Flint, J
Publicat: (2008)

Mapping Quantitative Trait Loci for Soybean Seedling Shoot and Root Architecture Traits in an Inter-Specific Genetic Population
per: Silvas J. Prince, et al.
Publicat: (2020-08-01)

Finding the molecular basis of quantitative traits: successes and pitfalls.
per: Flint, J, et al.
Publicat: (2001)

Genetic architecture of natural variation of cardiac performance from flies to humans
per: Saswati Saha, et al.
Publicat: (2022-11-01)

Simulating the collaborative cross: power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice.
per: Valdar, W, et al.
Publicat: (2006)

Distinct genetic architectures for male and female inflorescence traits of maize.
per: Patrick J Brown, et al.
Publicat: (2011-11-01)

The genetic architecture of psychophysiological phenotypes.
per: Munafò, MR, et al.
Publicat: (2014)

A simple genetic basis for a complex psychological trait in laboratory mice.
per: Flint, J, et al.
Publicat: (1995)

Quantitative trait locus mapping in laboratory mice derived from a replicated selection experiment for open-field activity.
per: Turri, MG, et al.
Publicat: (2001)

Quantitative Genetic Dissection of Shoot Architecture Traits in Maize: Towards a Functional Genomics Approach
per: Nick Lauter, et al.
Publicat: (2008-11-01)

Genome-wide genetic association of complex traits in heterogeneous stock mice.
per: Valdar, W, et al.
Publicat: (2006)

Strategies for mapping and cloning quantitative trait genes in rodents.
per: Flint, J, et al.
Publicat: (2005)

Genetic architectures of the human hippocampus and those involved in neuropsychiatric traits
per: Caibo Ning, et al.
Publicat: (2024-10-01)

Genetic interactions with sex make a relatively small contribution to the heritability of complex traits in mice
per: Krohn, J, et al.
Publicat: (2014)

Genetic architecture of fruit yield and its contributing quantitative traits in Abelmoschus esculentus (L.) Moench
per: Khanorkar S.M. and K. B. Kathiria
Publicat: (2010-07-01)

Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus.
per: Fullerton, J, et al.
Publicat: (2008)

A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
per: Solberg, L, et al.
Publicat: (2006)

A population genetic interpretation of GWAS findings for human quantitative traits.
per: Yuval B Simons, et al.
Publicat: (2018-03-01)

Applying mouse complex-trait resources to behavioural genetics.
per: Flint, J, et al.
Publicat: (2008)

Anxiety in genetically heterogeneous rats: Towards the identification of quantitative genes for behavioural traits
per: López-Aumatel, R, et al.
Publicat: (2009)

Cryptic genetic variation of expression quantitative trait locus architecture revealed by genetic perturbation in <i>Caenorhabditis elegans</i>
per: Marijke H van Wijk, et al.
Publicat: (2023-03-01)

Large-scale genetic analysis of quantitative traits
per: Randall, J, et al.
Publicat: (2012)