Cloning and characterisation of myospryn, a novel dysbindin-binding protein in muscle
Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease caused by mutations in the gene encoding dystrophin. Loss of dystrophin leads to the disruption of the dystrophin-associated glycoprotein complex (DGC), membrane fragility and increased intracellular calcium. Disruption of the DGC h...
Main Authors: | , |
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Format: | Thesis |
Language: | English |
Published: |
2005
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