Metal-free oxidative fluorination of phenols with [18F]fluoride.
The radiochemical synthesis of [18F]4-fluorophenols is based on phenol umpolung under oxidative conditions and direct nucleophilic fluorination with [18F]fluoride (see scheme, TBAF=tetra-n-butylammonium fluoride, TFA=trifluoroacetic acid). Readily available O-unprotected 4-tert-butyl phenols are use...
Egile Nagusiak: | , , , , , , , , , , |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2012
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